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Directory > LDN > Links
Opening hours: Mon: 2pm-6pm Tue-Sat: 9:30am - 6pm
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LDN - Low-Dose Naltrexone Just over 2 years ago we received a query about Low Dose Naltrexone; the use of a Narcotic Blocker, Naltrexone, at a much lower dose to help in the treatment of Multiple Sclerosis. Since then we have completed a lot of research and training to learn how to make this drug ourselves in capsule form, in any strength required by prescribers. There is a lot of information available, much of it based on speculation, and conjecture. The drug though has been seen to be very beneficial in many “auto-immune” type conditions, and the evidence is there for all to see. It must be remembered that all these uses are “off label” or unlicensed uses of this drug. The links to the best resources and information are contained in this section as well as some Q and A’s and some basic information What is LDN? Naltrexone itself was approved by the FDA in 1984 in a 50mg dose for the purpose of helping heroin or opium addicts, by blocking the effect of such drugs. By blocking opioid receptors, naltrexone also blocks the reception of the opioid hormones that our brain and adrenal glands produce: beta-endorphin and metenkephalin. Many body tissues have receptors for these endorphins and enkephalins, including virtually every cell of the body's immune system. In 1985, Bernard Bihari, MD, a physician with a clinical practice in New York City, discovered the effects of a much smaller dose of naltrexone (approximately 3mg once a day) on the body's immune system. He found that this low dose, taken at bedtime, was able to enhance a patient's response to infection by HIV, the virus that causes AIDS. [Note: Subsequently, the optimal adult dosage of LDN has been found to be 4.5mg.] In the mid-1990's, Dr. Bihari found that patients in his practice with cancer (such as lymphoma or pancreatic cancer) could benefit, in some cases dramatically, from LDN. In addition, people who had an autoimmune disease (such as lupus) often showed prompt control of disease activity while taking LDN. Read more at www.lowdosenaltrexone.org. |
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